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7 nM and 14 nM
59865-13-3
Chemical Name: 1-Methyl-7-nitro-2H-3
but also to a novel-binding pocket
InChiKey: NMUSYJAQQFHJEW-KVTDHHQDSA-N
IACS-9571 - CAS# 1800477-30-8 size:10mg solid 7 nM and 14 nMIACS 9571, CAS No. 1800477 30 8, is a potent and selective inhibitor TRIM24 and BRPF1. IACS 9571 has low nanomolar affinities for TRIM24 and BRPF1 (ITC Kd = 31 nM and 14 nM, respectively). With its excellent cellular potency (EC50 = 50 nM) and favorable pharmacokinetic properties (F = 29%), IACS 9571 is a high quality chemical probe for the evaluation of TRIM24 and or BRPF1 bromodomain function in vitro and in vivo. Product information CAS Number:
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