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Astilbin is a flavonoid compound that can enhance NRF2 activition with anti-inflammatory properties
BMS-626529 had half-maximal effective concentration (EC(50)) values of <10 nM against the vast majority of viral isolates
Smiles: OC1(CCC(CC1)N[C@@H]1CN(CC1)C(=O)CNC(=O)C1=CC(=CC=C1)C(F)(F)F)C1=CC=C(C=N1)C1N=CC=CN=1
Compared with other subtype-selective ligands
Ondansetron is a highly specific and selective serotonin 5-HT3 receptor antagonist (Ki=6
SB-742457 ndigo Astilbin is a flavonoid compoundIntepirdine, also known as SB 742457 and RVT 101, is a selective 5 HT6 receptor antagonist with potential cognition, memory, and learning enhancing effects. It was under development by GlaxoSmithKline for the treatment of Alzheimer's disease and demonstrated some preliminary efficacy in phase II clinical trials. SB742457 can reverse age related declines in delayed non match to sample performance (DNMS). SB742457 shows increasing pro cognitive effects
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