BAY-85-8501 osuccinimidyl oleate Interaction of Trastuzumab with the

Interaction of Trastuzumab with the human immune system via its human immunoglobulin G1 Fc domain may potentiate its antitumor activities

InChi: InChI=1S/C20H21F2N9O9P2S2/c21-9-13-7(37-19(9)30-5-28-11-15(23)24-3-25-16(11)30)1-35-42(34

57(21):4838-48

The most unique feature is the relative terminal long half-life of about 26 hours

From 4 to 8 hours the drug plasma levels drops to 0

BAY-85-8501 osuccinimidyl oleate Interaction of Trastuzumab with theBAY 85 8501 is a selective, reversible and potent inhibitor of Human Neutrophil Elastase (HNE), with an IC50 of 65 pM. Product information CAS Number: 1161921 82 9 Molecular Weight: 474. 46 Formula: C22H17F3N4O3S Chemical Name: (4S) 4 (4 cyano 2 methanesulfonylphenyl) 3,6 dimethyl 2 oxo 1 [3 (trifluoromethyl)phenyl] 1,2,3,4 tetrahydropyrimidine 5 carbonitrile Smiles: CN1[C@@H](C(C#N)=C(C)N(C1=O)C1C=C(C=CC=1)C(F)(F)F)C1=CC=C(C=C1S(C)(=O)=O)C#N