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11)12)2-5(6(4)8)16(10
Chemical Name: 4-(2-aminoethoxy)-N2
5 nM (PKC-ε)
3 μM and in UM-UC-14 cells 52
Formula: C29H48O
DT2216 60031 11)12)2-5(6(4)8)16(10DT2216 is a potent and selective degrader of BCL XL based on PROTAC technology. DT2216 inhibits various BCL XL dependent leukemia and cancer cells but considerably less toxic to platelets. Product information CAS Number: 2365172 42 3 Molecular Weight: 1542. 36 Formula: C77H96ClF3N10O10S4 Chemical Name: (2S,4R) 1 ((S) 2 (7 (4 ((R) 3 ((4 (N (4 (4 ((4' chloro 4,4 dimethyl 3,4,5,6 tetrahydro [1,1' biphenyl] 2 yl)methyl)piperazin 1 yl)benzoyl)sulfamoyl) 2