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4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-6-(oxetan-3-ylamino)pyrimidine-4-carboxamide
Smiles: CN(C)[C@@H]1CC2C=CC=C(C3C(C)=NN(C)C=3C)C=2CC1
potent LPA1(Lysophosphatidic Acid Receptor) antagonist with an IC50 of 160 nM
The growth of human malignant melanoma xenografts
is an orally bioavailable specific oral inhibitor of the pan-class I phosphatidylinositol 3-kinase (PI3K) family of lipid kinases with potential antineoplastic activity
PROTAC EED degrader-2 17259 4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-6-(oxetan-3-ylamino)pyrimidine-4-carboxamidePROTAC EED degrader 2 is a PROTAC targeting EED with a pKD of 9. 27. PROTAC EED degrader 2 is a polycomb repressive complex 2 (PRC2) inhibitor (pIC50=8. 11) targeting the EED subunit. Product information CAS Number: 2639882 69 0 Molecular Weight: 960. 13 Formula: C50H58FN11O6S Chemical Name: (2S, 4R) 1 [(2S) 2 (5 {3 [5 (5 {[(5 fluoro 2, 3 dihydro 1 benzofuran 4 yl)methyl]amino} [1, 2, 4]triazolo[4, 3 c]pyrimidin 8 yl) 6 methylpyridin 2