PF-AKT400 omanol 293B 5]undecan-3-yl]prop-1-yn-1-yl}-7-methoxyisoquinoline-6-carboxamide

5]undecan-3-yl]prop-1-yn-1-yl}-7-methoxyisoquinoline-6-carboxamide

Tariquidar (XR9576) is a potent modulator of P-gp mediated [3H]-Vinblastine and [3H]-Paclitaxel transport as it increases the steady-state accumulation of these cytotoxics in CHrB30 cells to levels observed in non-P-gp-expressing AuxB1 cells (EC50=487±50 nM)

22(6):810-8

Linalool is a PPARα ligand that reduces plasma TG levels and rewires the hepatic transcriptome and plasma metabolome

4-b]pyridin-6-yl]methoxy}piperidine-1-carboxylate

PF-AKT400 omanol 293B 5]undecan-3-yl]prop-1-yn-1-yl}-7-methoxyisoquinoline-6-carboxamidePF AKT400 is a broadly selective, potent, ATP competitive Akt inhibitor, displays 900 fold greater selectivity for PKB (IC50=0. 5 nM) than PKA (IC50=450 nM). Product information CAS Number: 1004990 28 6 Molecular Weight: 400. 43 Formula: C20H22F2N6O Chemical Name: N {[(3S) 3 amino 1 {5 ethyl 7H pyrrolo[2,3 d]pyrimidin 4 yl}pyrrolidin 3 yl]methyl} 2,4 difluorobenzamide Smiles: CCC1=CNC2=NC=NC(=C21)N1C[C@@](N)(CNC(=O)C2=CC=C(F)C=C2F)CC1 InChiKey: