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23)18-6-2-5-17(21)14-18
Discovery of novel resorcinol diphenyl ether-based PROTAC-like molecules as dual inhibitors and degraders of PD-L1
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InChiKey: HESLKTSGTIBHJU-UHFFFAOYSA-N
EC 690-730-1
Mutated EGFR-IN-2 - CAS# 2050906-97-1 Size:Contact [email protected] for quotation 23)18-6-2-5-17(21)14-18Mutated EGFR IN 2 (compound 91) is a mutant selective EGFR inhibitor extracted from patent WO2017036263A1, which potently inhibits single mutant EGFR (T790M) and double mutant EGFR (including L858R T790M (IC50=1nM) and ex19del T790M), and can suppress activity of single gain of function mutant EGFR (including L858R and ex19del) as well. Mutated EGFR IN 2 shows anti tumor antivity. Product information CAS Number: 2050906 97 1 Molecular Weight: 562. 64