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JIB-04 (NSC693627
including programmed cell death 1 ligand 1 (PD-L1)
These protective effects are related to its ability to attenuate oxidative stress
and shows minor toxicity by the oral route when administered as Cloperastine fendizoate
and does not potently inhibit PI3K
KO-947 3-amine JIB-04 (NSC693627KO 947 is a potent and selective inhibitor of ERK1 2 kinases. KO 947 blocks ERK signaling and proliferation of tumor cells exhibiting dysregulation of MAPK pathway signaling at low nanomolar concentrations. Product information CAS Number: 1695533 89 1 Molecular Weight: 355. 39 Formula: C21H17N5O Chemical Name: 1,5,6,8 Tetrahydro 6 (phenylmethyl) 3 (4 pyridinyl) 7H pyrazolo[4,3 g]quinazolin 7 one Smiles: