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11-tetraen-15-yl]-2-methylbut-2-enoic acid
Smiles: CN(C)[C@H]1CC2C3=CC(=CC=C3NC=2CC1)NC(=O)C1C=CC(F)=CC=1
whereas other transformed and normal human cells are several orders of magnitude less sensitive
It is used to treat many infections including treatment of respiratory
J Comput Aided Mol Des
SB 242084 Catalog No.:M21140-C 11-tetraen-15-yl]-2-methylbut-2-enoic acidSB 242084 is a 5 HT2C receptor antagonist(pKi=9. 0) that displays 158 and 100 fold selectivity over 5 HT2A and 5 HT2B receptors respectively. IC50 value: 9. 0(pKi) Target: 5 HT2C antagonistin vitro: SB 242084 had over 100 fold selectivity over a range of other 5 HT, dopamine and adrenergic receptors. In studies of 5 HT stimulated phosphatidylinositol hydrolysis using SH SY5Y cells stably expressing the cloned human 5 HT2C receptor, SB 242084 acted as
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