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6 and 6 nM for ROCK-I and ROCK-II
leading to a disruption of cell cycle progression
2007 May 17
It was approved by the Food and Drug Administration (FDA) on June 23
01 nM-10 μM) displaces the binding of the allosteric binding ligand [3H]-AAE327 in a concentration-dependent manner in rat brain membranes
Jatrorrhizine chloride Size:Contact [email protected] for quotation 6 and 6 nM forJatrorrhizine chloride is an alkaloid isolated from Coptis chinensis with neuroprotective, antimicrobial, antiplasmodial and antioxidant activities. Jatrorrhizine chloride is a potent and orally active inhibitor of AChE (IC50=872 nM) over >115 fold selectivity for BuChE. Jatrorrhizine chloride reduces uptake of serotonin (5 HT) and norepinephrine (NE) via inhibition of uptake 2 transporters. Product information CAS Number: 6681 15 8 Molecular Weight:
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