JAK2/FLT3-IN-1 TFA 13224 aeruginosa PAO1 and PA14 strains

aeruginosa PAO1 and PA14 strains

and PKC with 1000-fold or greater IC50 values

AZD-8529 is a potent

methyl (2S)-2-[(2S)-2-amino-4-methylpentanamido]-4-methylpentanoate

Smiles: CC(C)C(NC(=O)C(CC(O)=O)NC(=O)C(CC1C=CC(O)=CC=1)NC(=O)C1CCCN1C(=O)C(N)CC1C=CC(O)=CC=1)C(=O)N1CCCC1C(=O)NC(CC(O)=O)C(=O)NC(CC1C=CC(O)=CC=1)C(=O)NC(C)C(O)=O

JAK2/FLT3-IN-1 TFA 13224 aeruginosa PAO1 and PA14 strainsJAK2 FLT3 IN 1 (TFA) is a potent and orally active dual JAK2 FLT3 inhibitor with IC50 values of 0. 7 nM, 4 nM, 26 nM and 39 nM for JAK2, FLT3, JAK1 and JAK3, respectively. JAK2 FLT3 IN 1 (TFA) has anti cancer activity. Product information CAS Number: 2928093 29 0 Molecular Weight: 581. 61 Formula: C27H35F4N7O3 Chemical Name: 2 ({1 [2 fluoro 4 ({5 methyl 4 [1 (propan 2 yl) 1H pyrazol 4 yl]pyrimidin 2 yl}amino)phenyl]piperidin 4 yl}(methyl)amino)ethan 1