![Rp-8-pCPT-Cyclic GMPS (sodium salt) 078esopitron dihydrochloride 3S)-3-{[(1S)-1-({4-[(diaminomethylidene)amino]butyl}carbamoyl)-3-methylbutyl]carbamoyl}oxirane-2-carboxylic acid](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M23095_1635336502.gif?v=1635336504)
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3S)-3-{[(1S)-1-({4-[(diaminomethylidene)amino]butyl}carbamoyl)-3-methylbutyl]carbamoyl}oxirane-2-carboxylic acid
CL14377 disodium
InChi: InChI=1S/C22H24O4S/c1-14-12-16(13-15(2)20(14)26-22(3
CAS Number: 1912-33-0
It showed a broad anti-inflammatory profile in a LPS-challenged Balb/C mouse model
Rp-8-pCPT-Cyclic GMPS (sodium salt) 078esopitron dihydrochloride 3S)-3-{[(1S)-1-({4-[(diaminomethylidene)amino]butyl}carbamoyl)-3-methylbutyl]carbamoyl}oxirane-2-carboxylic acidIC50: 18. 3 and 0. 16 M for cGK I and cGK II, respectively. Rp 8 pCPT Cyclic GMPS is a GMP dependent protein kinases (cGKs) inhibitor. Appreciation of cGMP as a distinct intracellular second messenger is reported to be closely followed by an intensive search for effector proteins in various organisms. A cGMP dependent protein kinase (cGK) has been found in arthropods resulting in the eventual isolation of cGK from mammalian tissues. In vitro: Previous
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