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Itraconazole-d5 oxy-3-prenylnaphthalene-1-O-β-D-glucopyranoside 294(18):7377-7387

SKU: 72674657190

4.9
USD100.00 USD145.00

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Description

294(18):7377-7387

InChiKey: UNPLRYRWJLTVAE-UHFFFAOYSA-N

Datelliptium acetate is highly active against early-stage colon #38 with highest non-toxic dose (HNTD) of 170 mg/kg TD

Braddock M

Smiles: O=C1NC(=O)C(F)=CN1C(=O)NC1C=CC=CC=1

Itraconazole-d5 oxy-3-prenylnaphthalene-1-O-β-D-glucopyranoside 294(18):7377-7387Itraconazole d5 (R51211 d5) is the deuterium labeled Itraconazole. Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ~800 nM. Itraconazole potently inhibits lanosterol 14 demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Product information CAS

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