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3-benzodiazole-7-carboxylic acid
Chemical Name: dimethyl[1-(10H-phenothiazin-10-yl)propan-2-yl]amine hydrochloride
CAS Number: 85081-18-1
3]dioxol-5-yl)-5-(pyridin-2-yl)-1H-imidazol-2-yl)benzamide
Formula: C48H68N14O14S2
A-317491 sodium salt hydrate thalin 3-benzodiazole-7-carboxylic acidA 317491 sodium salt hydrate is a non nucleotide P2X3 and P2X2 3 receptor antagonist, which inhibits calcium flux mediated by the receptors. IC50 value: Target: P2X2 3 receptor It is known that P2X3 and P2X2 3 receptors stimulate the pronociceptive effects of ATP upon activation. Studies indicate that the P2X3 receptor is implicated in both neuropathic and inflammatory pain. P2X3 receptor is a promising target for therapeutic intervention in cancer
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