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Peak plasma and tissue concentrations are seen at 5 minutes after dosing except for the small intestine (4 hrs) and abdominal fat
Smiles: CN(CCCCCCOC1C=C(F)C(=CC=1)C(=O)C1C=CC(Br)=CC=1)CC=C
with a Ki of 26 nM for hY5
20-lyase and 17α-hydroxylase with IC50 of 27 and 30 nM respectively
1863(2):598-606
FHT-1015 bufen Peak plasma and tissue concentrationsFHT 1205 is a potent SMARCA4 SMARCA2 ATPase (BRG1 and BRM) inhibitor with IC50s of 10 nM (WO2020160180A1; compound 67). Product information CAS Number: 2368903 18 6 Molecular Weight: 555. 69 Formula: C25H25N5O4S3 Smiles: CSCC[C@H](NC(=O)C1=CN(C=C1)S(C)(=O)=O)C(=O)NC1=NC(=CS1)C1=CC(=CC=C1)C1C=CN=CC=1 InChiKey: FAYSHZVDWADZMD NRFANRHFSA N InChi: InChI=1S C25H25N5O4S3 c1 35 13 9 21(27 23(31)20 8 12 30(15 20)37(2,33)34)24(32)29 25 28 22(16 36 25)19 5 3 4
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