MLN-4760 3237 Smiles: CC1C(=CC=CC=1C1=CN(C)C(=O)C(NC2=CC=C(C=C2)[C@H]2C(=O)N(C)CCN2C)=N1)NC(=O)C1=CC2CCCCC=2S1

Smiles: CC1C(=CC=CC=1C1=CN(C)C(=O)C(NC2=CC=C(C=C2)[C@H]2C(=O)N(C)CCN2C)=N1)NC(=O)C1=CC2CCCCC=2S1

InChiKey: YYNRZIFBTOUICE-UHFFFAOYSA-N

giving an explanation of the resistance of PTEN- cells to PLX-4720-induced apoptosis

also known as BMY 26517

Manzamine A hydrochloride targets vacuolar ATPases and inhibits autophagy in pancreatic cancer cells

MLN-4760 3237 Smiles: CC1C(=CC=CC=1C1=CN(C)C(=O)C(NC2=CC=C(C=C2)[C@H]2C(=O)N(C)CCN2C)=N1)NC(=O)C1=CC2CCCCC=2S1MLN 4760 is a potent and selective human ACE2 inhibitor (IC50, 0. 44 nM), with excellent selectivity (>5000 fold) versus related enzymes including human testicular ACE (IC50, >100 M) and bovine carboxypeptidase A (CPDA; IC50, 27 M). Product information CAS Number: 305335 31 3 Molecular Weight: 428. 31 Formula: C19H23Cl2N3O4 Chemical Name: (2S) 2 {[(1S) 1 carboxy 2 {1 [(3,5 dichlorophenyl)methyl] 1H imidazol 5 yl}ethyl]amino} 4 methylpentanoic acid