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and has weaker activity against monoamine oxidase proteins MAO-A and MAO-B with IC50 ~0
33 mg/mL (250
InChiKey: PUYVJBBSBPUKBT-UHFFFAOYSA-N
Neitzel LR
18(5):1691-6
YK-4-279 - CAS# 1037184-44-3 Catalog No.:M10399-2 and has weaker activity againstYK 4 279 is a ETV1 inhibitor, which inhibitor protein protein interactions between ES FLI1 and RHA. YK 4 279 effectively antagonizes EWS FLI1 induced leukemia in a transgenic mouse model. YK 4 279 demonstrates specificity in targeting the oncogene EWS FLI1. YK 4 279, prevents prostate cancer growth and metastasis in a mouse xenograft model. Product information CAS Number: 1037184 44 3 Molecular Weight: 366. 20 Formula: C17H13Cl2NO4 Synonym: YK 4 279
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