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Loxapine succinate - CAS# 27833-64-3 oxy)-1 6-dihydroxy-2-methyl-9 10-anthracenedione InChiKey: WZUODJNEIXSNEU-UHFFFAOYSA-N

SKU: 71051493877

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Description

InChiKey: WZUODJNEIXSNEU-UHFFFAOYSA-N

Smiles: CC(C)OC(=O)[C@H](C)N[P@](=O)(OC[C@H]1O[C@@H](N2C=CC(=O)NC2=O)[C@@](C)(F)[C@H]1O)OC1=CC=CC=C1

InChiKey: SDGDWRYYHQOQOJ-QBGQQMMYSA-N

PubMed PMID: 15698853

CAS Number: 73963-72-1

Loxapine succinate - CAS# 27833-64-3 oxy)-1 6-dihydroxy-2-methyl-9 10-anthracenedione InChiKey: WZUODJNEIXSNEU-UHFFFAOYSA-NLoxapine Succinate is a D2DR and D4DR inhibitor, serotonergic receptor antagonist and also a dibenzoxazepine anti psychotic agent. IC50 value: Target: D2DR D4DR; 5 HT receptor in vitro: In the presence of Loxapine, [3H]ketanserin binds to 5 HT2 receptor in Frontal cortex of brain in human and bovine with ki value of 6. 2 nM and 6. 6 nM, respectively. Loxapine has the rank order of potency for the various receptors appears to be as follows: 5

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