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It is licensed only for the treatment of chronic obstructive pulmonary disease (COPD) (long-term data in patients with asthma are thus far lacking)
24(6):791-805
Smiles: CC(C)N1C=NC2=C(NCCC3C=CC(O)=CC=3)N=C(N=C12)C1=CSC2=CC=CC=C21
0 pM (-pIC50±SEM: 10
26(2):158-9
Atrasentan Hydrochloride K inhibitor 4 (trans) It is licensed only forAtrasentan, also known as ABT 627, is a orally available ETA receptor antagonist with potential antineoplastic activity. As a selective antagonist of the endothelin A (ETA) receptor, atrasentan binds selectively to the ETA receptor, which may result in inhibition of endothelin induced angiogenesis and tumor cell proliferation. Product information CAS Number: 195733 43 8 Molecular Weight: 547. 08 Formula: C29H39ClN2O6 Chemical Name: (2R,3R,4S) 4 (2H