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AZD9291 is highly active in preclinical models and is well tolerated in animal models
10)/b11-6+
regulate colonic epithelial wound healing
de Oliveira AC
5(4):424-37
Rho-Kinase-IN-1 - CAS# 1035094-83-7 227 AZD9291 is highly active inRho Kinase IN 1, CAS No. 1035094 83 7, is a Rho kinase (ROCK) inhibitor (Ki values of 30. 5 and 3. 9 nM for ROCK1 and ROCK2, respectively) extracted from US20090325960A1, compound 1. 008. Product information CAS Number: 1035094 83 7 Molecular Weight: 352. 50 Formula: C20H24N4S Chemical Name: Rho Kinase IN 1 Smiles: CSC1=CC=C(CN2CC(CCC2)NC2C=C3C=NNC3=CC=2)C=C1 InChiKey: DPZSYTMLVCLGRU UHFFFAOYSA N InChi: InChI=1S C20H24N4S c1 25 19 7 4 15(5 8 19)13 24
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