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1640294-30-9
InChi: InChI=1S/C25H21N3O/c1-18-15-22(12-14-27-18)20-6-4-19(5-7-20)16-25(29)28-24-10-8-21(9-11-24)23-3-2-13-26-17-23/h2-15
A notable feature of ML323 is that it simultaneously targets two major DNA damage response pathways (TLS and FA) by inhibiting a common deubiquitinase
It blocks LPS-induced expression of inflammatory cytokines in human myelomonocytic cells
Effects of RAGE-Specific Inhibitor FPS-ZM1 on Amyloid-β Metabolism and AGEs-Induced Inflammation and Oxidative Stress in Rat Hippocampus
NS-2028 0280 1640294-30-9NS 2028 is a potent soluble guanylyl cyclase (sGC) inhibitor (Ki = 8 nM). It blocks sGC activity in murine cerebellum induced by S nitroso glutathione and NMDA (IC50 values are 17 and 20 nM respectively). NS 2028 also inhibits VEGF induced cGMP accumulation. Product information CAS Number: 204326 43 2 Molecular Weight: 269. 05 Formula: C9H5BrN2O3 Synonym: NS 2028 NS2028 Chemical Name: 8 bromo 4H [1, 2, 4]oxadiazolo[3, 4 c][1, 4]benzoxazin 1 one
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