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~340 nM for JMJD2E (KDM2E)
Epstein DL
3109/01902148
1352608-82-2
PMID: 33017361
Roflumilast N-oxide trabetan (BC-2059) ~340 nM for JMJD2E (KDM2E)Roflumilast N oxide an active metabolite of roflumilast is an inhibitor of phosphodiesterase 4 PDE4 It can be combined with formoterol to enhance the antiinflammatory effect of dexamethasone Product information CAS Number: 292135 78 5 Molecular Weight: 419. 21 Formula: C17H14Cl2F2N2O4 Chemical Name: N (3,5 Dichloro 1 oxopyridin 4 yl) 4 difluoromethoxy 3 cyclopropylmethoxybenzamide Smiles: [O ][N+]1C=C(Cl)C(NC(=O)C2=CC(OCC3CC3)=C(C=C2)OC(F)F)=C(Cl)C=1
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