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SB-242235 demonstrated non-linear elimination kinetics that manifested as a decrease in clearance with increasing dose and apparent oral bioavailability > 100% at high oral doses
GSK 2643943A
Smiles: CCC(=O)NCC[C@@H]1CCC2=CC=C3OCCC3=C21
CAS Number: 380607-77-2
AEE788 also inhibits KDR
JZL195 Catalog No.:M11137-2 SB-242235 demonstrated non-linear elimination kineticsJZL195 is a potent and selective dual inhibitor of FAAH and monacylglycerol lipase (MAGL). JZL195 has greater anti allodynic efficacy than selective FAAH, or MAGL inhibitors, plus a greater therapeutic window than a cannabinoid receptor agonist. JZL195 may have greater potential in alleviating neuropathic pain, compared to selective FAAH and MAGL inhibitors, or cannabinoid receptor agonists. Product information CAS Number: 1210004 12 8 Molecular
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