Tapinarof (WBI-1001) is a natural aryl hydrocarbon receptor (AhR) agonist with an EC50 of 13 nM
Chemical Name: (2E)-3-(1-{4-[(dimethylamino)methyl]benzenesulfonyl}-1H-pyrrol-3-yl)-N-hydroxyprop-2-enamide hydrochloride
Smiles: CC1=CC(C)=C(CNC(=O)C2=CC(Cl)=C3O[C@@](C)(OC3=C2C)[C@@H]2CC[C@H](CC2)N(C)C)C(=O)N1
MK-571-treated mice display lower RVSP and Fulton index and a decrease in the medial thickening of small pulmonary arteries and arterioles
InChi: InChI=1S/C22H34O15/c1-6-9(24)2-7-8(19(31)32)4-33-20(12(6)7)37-22-18(30)16(28)14(26)11(36-22)5-34-21-17(29)15(27)13(25)10(3-23)35-21/h4
(Z)-Orantinib Size:Contact [email protected] for quotation Tapinarof (WBI-1001) is a natural(Z) Orantinib ((Z) SU6668) is a potent, selective, orally active and ATP competitive inhibitor of Flk1 KDR, PDGFR, and FGFR1, with IC50s of 2. 1, 0. 008, and 1. 2 M, respectively. (Z) Orantinib is a potent antiangiogenic and antitumor agent that induces regression of established tumors. Product information CAS Number: 210644 62 5 Molecular Weight: 310. 35 Formula: C18H18N2O3 Chemical Name: 3 (2,4 dimethyl 5 {[(3Z) 2 oxo 2,3 dihydro 1H indol 3