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Pamidronate (Disodium) Catalog No.:M11318-2 Specific inhibitors of the breast

SKU: 67701348872

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Description

Specific inhibitors of the breast cancer resistance protein (BCRP)

PubMed PMID: 21940661

InChiKey: JERZEQUMJNCPRJ-UHFFFAOYSA-N

Chemical Name: 5-cyano-2'-(4-(2-(3-methyl-1H-indol-1-yl)ethyl)piperazin-1-yl)-N-(3-(pyrrolidin-1-yl)propyl)-[1

2014 Nov 5

Pamidronate (Disodium) Catalog No.:M11318-2 Specific inhibitors of the breastPamidronate disodium is the disodium salt of the synthetic bisphosphonate pamidronate. Although its mechanism of action is not completely understood, pamidronate appears to adsorb to calcium phosphate crystals in bone, blocking their dissolution by inhibiting osteoclast mediated bone resorption. This agent does not inhibit bone mineralization and formation. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).

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