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349(2-3):237-43
InChiKey: PGZUMBJQJWIWGJ-ONAKXNSWSA-N
PROTAC ERRα Degrader-1 comprises a MDM2 ligand binding group
Mol Cancer Ther 2014
23)24)5-6-12(10)18-16)15-14(19-21)9-3-1-2-4-11(9)17-15/h1-7
Phthalimide-PEG4-PDM-OTBS CT007093 349(2-3):237-43Phthalimide PEG4 PDM OTBS is a PROTAC linker, which refers to the PEGs composition. Phthalimide PEG4 PDM OTBS can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin proteasome system to selectively degrade target proteins. Product information Molecular Weight: 536. 73