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A small molecule inhibitor of TGFß RI kinase potentiates VEGF dependent angiogenesis in vitro
Formula: C17H15FN2O3
Smiles: OC(=O)CCC1=C(NC2=CC(Cl)=CC(Cl)=C12)C(O)=O
selective and orally bioavailable DYRK1A inhibitor with IC50 of 80 nM
Formula: C16H15NO7S
Daminozide - KDM2/7 Histone Demethylases Inhibitor. CAS# 1596-84-5 size:10 mg solid A small molecule inhibitor ofDaminozide, CAS No. 1596 84 5, is a potent and selective small molecule inhibitor of the KDM2 7 family of human JmjC histone demethylases. It inhibits KDM2A at IC50 ~1. 5 M, PHF8 at IC50 ~0. 55 M, and KIAA1718 at IC50 ~2. 1 M. It has at least 60 fold selectivity as an inhibitor of the KDM2 7 subfamily over the other demethylase subfamily members such as KDM3A, KDM4E, KDM5C and KDM6B, and exhibits no inhibition even at 1 mM for PHD2, FIH, and BBOX1
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US$ 34000.00
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US$ 74000.00