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6-dihydro-[1
LY294002 was used at 10-50 µM final concentration in various in vitro assays
Pimecrolimus blocks T-lymphocyte activation pathway by inhibiting calcineurin function
8-di(H)methoxy-2
CAS Number: 1793053-37-8
LY-2584702 free base Size:Solid 10 mg 6-dihydro-[1LY 2584702, also known as LYS6K2, is an orally available inhibitor of p70S6K signaling, with potential antineoplastic activity. LY2584702 inhibits ribosomal protein S6 Kinase (p70S6K), and prevents phosphorylation of the S6 subunit of ribosomes, thereby inhibiting normal ribosomal function within tumor cells leading to a decrease in protein synthesis and in cellular proliferation. P70S6K, a serine threonine kinase, acts downstream of PIP3 and
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