L-701324 tone isopropyl 3-d]pyrimidine-6-carboxamide hydrochloride

3-d]pyrimidine-6-carboxamide hydrochloride

62(2):928-940

while it failed to displace [(3)H]LY341495 (a competitive mGlu2/3 receptor antagonist)

the limits are 100 μg/kg in muscle and milk

23-dioic acid compound with 2

L-701324 tone isopropyl 3-d]pyrimidine-6-carboxamide hydrochlorideL 701324 is an orally active and long acting anticonvulsant with high affinity and selectivity for the glycine site on the NMDA receptor. Target: NMDA ReceptorL 701324 is a potent, active anticonvulsant with a reduced propensity to activate mesolimbic dopaminergic systems in rodents. L 701324 exhibits a beneficial action in the animal model of parkinsonian rigidity, but not that of parkinsonian akinesia. L 701324 (2. 5 40 mg kg, i. p.) dose