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4-methyl Erlotinib 14591 4)23(38)10-13-40(24

SKU: 65476287927

4.1
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Description

4)23(38)10-13-40(24

CAS Number: 153252-36-9

NCC(O)C1=CC=C(O)C=C1

InChi: InChI=1S/C20H20F2N8O/c21-13-3-4-14-17(16(13)22)26-15(25-14)10-23-19-28-20(29-5-7-31-8-6-29)27-18-12(11-1-2-11)9-24-30(18)19/h3-4

9) inhibitor

4-methyl Erlotinib 14591 4)23(38)10-13-40(244 methyl Erlotinib is an analog of erlotinib by the addition of a methyl group at the four position of the phenyl group. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR) . The epidermal growth factor receptor (EGFR) autocrine pathway has been important for cancer development and progression, including cell proliferation, apoptosis, angiogenesis, and metastatic spread . Erlotinib inhibits EGFR

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