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Verucerfont is a corticotropin-releasing factor receptor 1 (CRF1) antagonist with IC50s of ~6
4-amino-1, 8-Naphthalimide Catalog No.:M22461-C Verucerfont is a corticotropin-releasing factor4 amino 1,8 Naphthalimide is a novel inhibitor of PARP with IC50 value of 180 nM . The poly(ADP ribose) polymerases (PARPs) is a nuclear enzyme that catalyzes a transfer of the ADP ribose moiety of NAD+ to acceptor protein with a concomitant release of nicotinamide. PARPs play important roles in DNA repair, cell differentiation, control of cell cycle, transformation, transcription, and alteration of chromatin architecture . 4 amino 1,8 Naphthalimide
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