AV-412 - CAS# 451493-31-5 Catalog No.:M10577-10 It has been shown to

It has been shown to significantly reduce intracellular reactive oxygen species (ROS) production and Ca2+ influx induced by glutamate

PubMed PMID: 26668189

CAS Number: 309928-48-1

PubMed PMID: 23920374

Zyflo sodium

AV-412 - CAS# 451493-31-5 Catalog No.:M10577-10 It has been shown toAV 412, also known as MP 412, is a second generation, orally bioavailable dual kinase inhibitor with potential antineoplastic activity. EGFR HER2 inhibitor AV 412 binds to and inhibits the epidermal growth factor receptor (EGFR) and the human epidermal growth factor receptor 2 (HER2), which may result in the inhibition of tumor growth and angiogenesis, and tumor regression in EGFR HER2 expressing tumors. This agent may be active against EGFR HER2