Temocapril Hydrochloride Catalog No.:M9100-10 1(1):51-67

1(1):51-67

1]heptane-2-carboxylic acid

5 μM) induces loss of viability and caspase 3/7 activation

and VEGF1 in the liver is noted for Dp44mT- and 3-AP (12 mg/kg per day)-treated animals

is a potent MRTF/SRF inhibitor

Temocapril Hydrochloride Catalog No.:M9100-10 1(1):51-67Temocapril is a prodrug of the ACE inhibitor, temocaprilat (IC50 = 3. 6 and 7. 6 nM in isolated rat lung and aorta, respectively). 1 Upon oral administration it is rapidly deesterified to the active form, which remains long acting until excreted in bile and urine. 1 In clinical trials, it has been used to reduce blood pressure, improve endothelial dysfunction, and prevent vascular remodeling, as well as improve insulin sensitivity and renal function