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3-d]pyrimidin-5-one
CMPD101 (100 μM
Smiles: CN1C(=NC2=CC=CC=C12)C1C=C2C(N=C(CCC)N2CC2=CC=C(C=C2)C2=CC=CC=C2C(O)=O)=C(C)C=1
Planta Med
Sardomozide HCl
NBD-556 tisone 3-d]pyrimidin-5-oneNBD 556 is a HIV 1 entry inhibitor. NBD 556 inhibited cellcell fusion between H9 HIV 1IIIB and MT 2 (IC50 ~3 M). NBD 556 prevent gp120 binding to CD4. The HIV 1 entry into host cells is a complex, multi factors involved, and multi step process. Especially, the attachment of HIV 1 envelope glycoprotein gp120 to the host cell receptor CD4 is the first key step during entry process, representing a promising antiviral therapeutic target. Product
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