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Abemaciclib for the treatment of breast cancer
Formula: C95H145ClF3N23O23S2
Yahav Dikshtein
It incorporates an E3 ligase ligand plus a PEG4 linker with terminal carboxylic acid ready for conjugation to a target protein ligand It is part of a range of functionalized tool molecules for PROTAC R&D
It comprises a ligand for von-Hippel Lindau (VHL) protein joined by a linker to a TBK1-targeting moiety
Clozapine D8 - CAS# 1185053-50-2 5139 Abemaciclib for the treatment ofClozapine D8 (HF 1854 D8) is the deuterium labeled Clozapine. Clozapine, an antipsychotic, is a potent antagonist of dopamine and a number of other receptors, with a Ki of 9. 5 nM for muscarinic M1 receptor. Clozapine is also a potent and selective agonist at the muscarinic M4 receptor (EC50=11 nM). Product information CAS Number: 1185053 50 2 Molecular Weight: 334. 87 Formula: C18H19ClN4 Chemical Name: 6 chloro 10 [4 methyl(2,2,3,3,5,5,6,6
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