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TGX221 blocks xenograft tumor growth of prostate cancer in nude mice
Chemical Name: 7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7
Azuprostat
InChi: InChI=1S/C32H35N5O5/c1-18-12-23(29(34)38)13-19(2)24(18)15-26(33)31(39)37(17-21-10-11-28(42-4)25(14-21)32(40)41)20(3)30-35-16-27(36-30)22-8-6-5-7-9-22/h5-14
4 and 8 µM of Salinomycin for 48 h show a dose-dependent reduction in cell number and a change in cell morphology
7-Octynoic acid - CAS# 10297-09-3 icosulfate TGX221 blocks xenograft tumor growth7 Octynoic acid (compound 42) is a PROTAC linker and can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin proteasome system to selectively degrade target proteins. Product information CAS Number: 10297 09 3 Molecular Weight: 140. 18 Formula: C8H12O2 Chemical Name:
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