Flavopiridol Hydrochloride 0261 3PO reduces glycolytic flux and

3PO reduces glycolytic flux and suppresses glucose uptake

Feldman ME

Metformin (2 mM) also increases threonine 172 phosphorylation in muscle cells

Smiles: CC1C=C(OCCN2C=C(C(O)=O)C3=CC=CC=C23)C(C)=CC=1

WO 2010022355 A1 20100225

Flavopiridol Hydrochloride 0261 3PO reduces glycolytic flux andFlavopiridol Hydrochloride (Alvocidib Hydrochloride) is a broad inhibitor of CDK, competing with ATP to inhibit CDKs including CDK1, CDK2, CDK4 with IC50s of 30, 170, 100 nM, respectively. Product information CAS Number: 131740 09 5 Molecular Weight: 438. 30 Formula: C21H21Cl2NO5 Synonym: Alvocidib hydrochloride Flavopiridol HL 275 HL 275 HMR 1275 HMR 1275 L 86 8275 L86 8275 MDL 107826A MDL 107826A NSC 649890 MDL 107, 826A Related CAS Number: 146426