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Oxindole (Indolin-2-one) vinostat) 5-benzyloxygramine stabilizes the N-NTD dimers

SKU: 58766288717

4.6
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Description

5-benzyloxygramine stabilizes the N-NTD dimers through simultaneous hydrophobic interactions with both partners

InChi: InChI=1S/C21H22N2O3/c1-4-14-10-9-13-16-17(14)19(24)18(20(25)22(16)3)21(26)23(5-2)15-11-7-6-8-12-15/h6-13

Smiles: OC1=C(NC2=CC=CC=C21)C1=NC2=CC=CC=C2C1=O

Formula: C16H11FN6O

InChiKey: NYNZQNWKBKUAII-KBXCAEBGSA-N

Oxindole (Indolin-2-one) vinostat) 5-benzyloxygramine stabilizes the N-NTD dimersOxindole (Indolin 2 one) is an aromatic heterocyclic building block. 2 indolinone derivatives have become lead compounds in the research of kinase inhibitors. Oxindole (Indolin 2 one) is a bicyclic structure consisting of a benzene ring fused to 2 pyrrolidone. Substituted indolinones can be referred as 'privileged structures' owing to their excellent binding affinity for many receptors and to the number of approved drugs containing this scaffold.

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