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Formula: C14H11Cl3N2O3
CC(=O)OC1=CC2CN(CCC=2S1)C(C1=CC=CC=C1F)C(=O)C1CC1
Epub 2017 Feb 9
Smiles: CC(C)(C)NCC(O)C1C=C(O)C=C(O)C=1
CAS Number: 1467093-03-3
Refametinib (R) 0531 Formula: C14H11Cl3N2O3Refametinib R enantiomer is a potent, selective and allosteric inhibitor of MEK1 2 in enzyme inhibition assays. Refametinib R has been reported to inhibit MEK activity and inhibit anchorage dependent growth. Moreover, it has shown a potent tumor growth inhibition (TGI) in the human A375 and colon carcinoma Colo205 tumor xenograft models. Product information CAS Number: 923032 38 6 Molecular Weight: 572. 34 Formula: C19H20F3IN2O5S Synonym: BAY 869766 R
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