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2ClH/c30-25-26(18-20-10-14-27-15-11-20
CAS Number: 518-69-4
2-dimethyl-2H
InChi: InChI=1S/C16H13NO7/c1-5(18)10-7(20)4-9-16(2
26)5/h16-17
FIIN-1 ide IV-A 2ClH/c30-25-26(18-20-10-14-27-15-11-20FIIN 1 is a potent, irreversible, selective FGFR inhibitor. FIIN 1 binds to FGFR1 2 3 4 and Flt1 4 with Kds of 2. 8 6. 9 5. 4 120 nM and 32 120 nM respectively. The biochemical IC50s of FIIN 1 are 9. 2, 6. 2, 11. 9, and 189 nM against FGFR1 2 3 4, respectively. Product information CAS Number: 1256152 35 8 Molecular Weight: 656. 60 Formula: C32H39Cl2N7O4 Chemical Name: N (3 {[3 (2,6 dichloro 3,5 dimethoxyphenyl) 7 {[4 (diethylamino)butyl]amino} 2 oxo