Sobetirome - CAS# 211110-63-3 inib (S) C#CCCC([O-])=O

C#CCCC([O-])=O

InChiKey: DKORMNNYNRPTBJ-UHFFFAOYSA-N

CEP-37440 is an orally available dual kinase inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase (ALK) and focal adhesion kinase (FAK)

Pelitinib at 75-500 nM also specifically inhibits the activation of AKT and ERK1/2

Formula: C20H21N5

Sobetirome - CAS# 211110-63-3 inib (S) C#CCCC([O-])=OSobetirome, also known as GC 1 and QRX 431, is a hyroid hormone beta receptor agonist. Sobetirome inhibits proliferation but induces differentiation and TR beta mRNA expression in mouse and rat osteoblast like cells. Sobetirome selectively binds to and activates TRbeta over TRalpha and this receptor selectivity led to the hypothesis that sobetirome would lower cholesterol through activation of liver TRbeta without stimulating cardiac function through