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ZL0420 exhibits submicromolar potency of inhibiting the TLR3-dependent innate immune gene program
Target: guanylate cyclase BAY 41-2272 is a recently introduced novel orally available agent that directly stimulates soluble guanylate cyclase (sGC) and sensitizes it to its physiological stimulator
InChi: InChI=1S/C18H11Cl2F4N5O/c19-10-3-1-2-9(4-10)16(30)27-17(25-13-6-11(20)5-12(21)7-13)26-15-8-14(28-29-15)18(22
049 mg/ mL) in LPS-activated J774
InChiKey: WDEYOYQVZPSNFR-UHFFFAOYSA-N
N-(acid-PEG3)-N-bis(PEG3-azide) 139al-PEG4-VC-PAB-DMEA-PNU-159682 ZL0420 exhibits submicromolar potency ofN (acid PEG3) N bis(PEG3 azide) is a PEG based PROTAC linker that can be used in the synthesis of PROTACs. Product information CAS Number: 2182602 17 9 Molecular Weight: 623. 70 Formula: C25H49N7O11 Chemical Name: 1 azido 12 (2 {2 [2 (2 azidoethoxy)ethoxy]ethoxy}ethyl) 3,6,9,15,18,21 hexaoxa 12 azatetracosan 24 oic acid Smiles: [N ]=[N+]=NCCOCCOCCOCCN(CCOCCOCCOCCC(O)=O)CCOCCOCCOCCN=[N+]=[N ] InChiKey: WDEYOYQVZPSNFR UHFFFAOYSA N InChi: InChI=1S
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