Palosuran improves pancreatic and renal function in diabetic rats
Necrotic cell death is determined by measuring lactate dehydrogenase (LDH) release from cells
InChi: InChI=1S/C17H20N2O
Chemical Name: 2-{[4-(pyridin-2-yl)piperazin-1-yl]methyl}-1H-1
Formula: C10H6O2
ML786 dihydrochloride Catalog No.:M19993-C Palosuran improves pancreatic and renalML786 dihydrochloride is a potent and orally bioavailable Raf inhibitor, with IC50s of 2. 1, 4. 2, and 2. 5 nM for V600EB Raf, wt B Raf, and C Raf, respectively. ML786 dihydrochloride also inhibits Abl 1, DDR2, EPHA2, KDR, and RET (IC50=<0. 5, 7. 0, 11, 6. 2, 0. 8 nM). ML786 dihydrochloride can be used for the research of cancers. Product information CAS Number: 1237536 18 3 Molecular Weight: 611. 48 Formula: C29H31Cl2F3N4O3 Chemical Name: (Z) 3 (2