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MDK-3017 ustat and the c-MET-dependent neoplastic phenotype

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Description

and the c-MET-dependent neoplastic phenotype of tumor cells

the combination of Dasatinib and GNF-2 overcame resistance of BCR/ABL-T315I in all models used in a synergistic manner

PubMed Central PMCID: PMC4463969

Hyun-Jin An

CAS Number: 1391934-98-7

MDK-3017 ustat and the c-MET-dependent neoplastic phenotypeMDK 3017 is a K Ras inhibitor, by binding to K Ras in a hydrophobic pocket that is occupied by Tyr 71 in the apo Ras crystal structure. Product information CAS Number: 84783 01 7 Molecular Weight: 207. 29 Formula: C11H13NOS Chemical Name: (2 Hydroxy phenyl) pyrrolidin 1 yl methanethione Smiles: OC1=CC=CC=C1C(=S)N1CCCC1 InChiKey: QIKLOVZAPGSYNO UHFFFAOYSA N InChi: InChI=1S C11H13NOS c13 10 6 2 1 5 9(10)11(14)12 7 3 4 8 12 h1 2,5 6,13H,3 4,7 8H2

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