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Smiles: CC1C=CC(=CC=1)C1=CSC(=N1)C1=CC(CCC)=NC=C1
but it is not used clinically for this purpose due to the discovery of brain lesions
Georgian Med News
MMLN2238-prodrug
is a potent
Rosuvastatin Calcium 60107 Smiles: CC1C=CC(=CC=1)C1=CSC(=N1)C1=CC(CCC)=NC=C1Rosuvastatin Calcium (Rosuvastatin hemicalcium) is a competitive HMG CoA reductase inhibitor with an IC50 of 11 nM. Rosuvastatin Calcium potently blocks human ether a go go related gene (hERG) current with an IC50 of 195 nM, delayed cardiac repolarization, and thereby prolonged action potential durations (APDs) and corrected QT interval (QTc) intervals. Rosuvastatin Calcium reduces the expression of the mature hERG and the interaction of heat shock
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