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inhibits DNA ligases I and III with IC50 of 10 μM and 10 μM
Both GTS-21 itself and its demethylated active metabolite 4-OH-GTS-21 display nootropic and neuroprotective effects
the reductions do not reach statistical significance compare with TP group
InChi: InChI=1S/C15H14O3/c1-15(2)8-7-11-13(17)12(16)9-5-3-4-6-10(9)14(11)18-15/h3-6H
5(11)12)2-4(9)10/h5-18H
Alpha-Estradiol Size:Contact [email protected] for quotation inhibits DNA ligases I andAlpha Estradiol is a weak estrogen and a 5 reductase inhibitor which is used as a topical medication in the treatment of androgenic alopecia. Product information CAS Number: 57 91 0 Molecular Weight: 272. 38 Formula: C18H24O2 Chemical Name: (1R,3aS,3bR,9bS,11aS) 11a methyl 1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH cyclopenta[a]phenanthrene 1,7 diol Smiles: C[C@]12CC[C@H]3[C@@H](CCC4C=C(O)C=CC=43)[C@@H]1CC[C@H]2O InChiKey: VOXZDWNPVJITMN SFFUCWETSA N