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12(4):299-304
5 μM and 1
PubMed Central PMCID: PMC4479529
Filippakopoulos
It can be used to functionally replace Dkk protein in blocking Wnt signaling in many assay conditions (e
FH535 - CAS# 108409-83-2 size:2mg solid 12(4):299-304FH535, CAS No. 108409 83 2, is a catenin pathway inhibitor. FH535 represses pancreatic cancer xenograft growth and angiogenesis. FH535 increases the radiosensitivity and reverses epithelial to mesenchymal transition of radioresistant esophageal cancer cell line KYSE 150R. FH535 inhibited metastasis and growth of pancreatic cancer cells. FH535 selectively inhibits cell proliferation and potentiates imatinib induced apoptosis in myeloid leukemia cell