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EGFR/ErbB-2/ErbB-4 inhibitor-2 Catalog No.:M14718-2 VU0467154 is a positive allosteric

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Description

VU0467154 is a positive allosteric modulator of the M4 muscarinic acetylcholine receptor (mAChR)

InChi: InChI=1S/C15H11F2N3/c16-11-3-1-10(2-4-11)8-18-15-13-7-12(17)5-6-14(13)19-9-20-15/h1-7

Arbutin is PLA2 and tyrosinase inhibitor found in Bergenia and Arctostaphylos used in skin whitening products

CAS Number: 74849-93-7

CP-724714 potently reduces the EGF-induced autophosphorylation of the chimera containing the erbB2 kinase domain at a concentration as low as 50 nmol/L (IC50=32 nM) but is markedly less potent against EGFR

EGFR/ErbB-2/ErbB-4 inhibitor-2 Catalog No.:M14718-2 VU0467154 is a positive allostericEGFR ErbB 2 ErbB 4 inhibitor 2 (Compound 5) is a EGFR and ErbB inhibitor with IC50s of 0. 017 M, 0. 08 M, 1. 91 M. Product information CAS Number: 179248 61 4 Molecular Weight: 387. 43 Formula: C23H21N3O3 Chemical Name: N [4 (benzyloxy)phenyl] 6,7 dimethoxyquinazolin 4 amine Smiles: COC1=CC2=NC=NC(NC3C=CC(=CC=3)OCC3C=CC=CC=3)=C2C=C1OC InChiKey: DNOKYISWMVFYFA UHFFFAOYSA N InChi: InChI=1S C23H21N3O3 c1 27 21 12 19 20(13 22(21)28 2)24 15 25 23(19)26 17

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