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Cumulatively these combined profiling technologies demonstrate that both JNK-IN-8 and JNK-IN-12 are remarkably selective covalent JNK inhibitors and are appropriate for interrogating JNK-dependent biological phenomena
InChi: InChI=1S/C11H6ClN3O6
K02288 reduces a robust phosphorylation of Smad1/5/8 induced by BMP4 stimulation
Entrectinib potently blocks proliferation of Ba/F3-TEL-TRKB (IC50 of 2
2015 Oct 17
Tinidazole Size:Solid 10 mg Cumulatively these combined profiling technologiesTinidazole is an antiprotozoal, antibacterial agent. The nitro group of tinidazole is reduced by cell extracts of Trichomonas. The free nitro radical generated as a result of this reduction may be responsible for the antiprotozoal activity. Chemically reduced tinidazole was shown to release nitrites and cause damage to purified bacterial DNA in vitro. Additionally, the drug caused DNA base changes in bacterial cells and DNA strand breakage in
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