Azido-PEG3-Sulfone-PEG4-acid (tert-butyldimethylsilyloxy) Efavirenz-d4 Smiles: NC1=C(SC2=NC3CCCC=3C=C21)C(=O)NC1C(Br)=CC(F)=CC=1F

Smiles: NC1=C(SC2=NC3CCCC=3C=C21)C(=O)NC1C(Br)=CC(F)=CC=1F

m-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs

2002 Aug 8

Smiles: [2H]C1([2H])N(C2=CC=CC=C2SC2=CC=C(C)C=C2C)C([2H])([2H])C([2H])([2H])NC1([2H])[2H]

with an IC50 of 5 μM and a Ki of 3

Azido-PEG3-Sulfone-PEG4-acid (tert-butyldimethylsilyloxy) Efavirenz-d4 Smiles: NC1=C(SC2=NC3CCCC=3C=C21)C(=O)NC1C(Br)=CC(F)=CC=1FAzido PEG3 Sulfone PEG4 acid is a PEG based PROTAC linker that can be used in the synthesis of PROTACs. Product information CAS Number: 2055024 42 3 Molecular Weight: 515. 58 Formula: C19H37N3O11S Chemical Name: 1 (2 {2 [2 (2 azidoethoxy)ethoxy]ethoxy}ethanesulfonyl) 3,6,9,12 tetraoxapentadecan 15 oic acid Smiles: [N ]=[N+]=NCCOCCOCCOCCS(=O)(=O)CCOCCOCCOCCOCCC(O)=O InChiKey: WDRWRFOESMUATQ UHFFFAOYSA N InChi: InChI=1S C19H37N3O11S c20 22 21 2 4 28 6 8